脱落酸介导胞内Ca<sup>2+</sup>参与调控灵芝三萜积累

崔美林; 赵燚涛; 张秀红; 赵微

doi:10.1631/jzus.B2300279

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脱落酸介导胞内Ca²⁺参与调控灵芝三萜积累

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Correspondence | Updated：2024-01-19

脱落酸介导胞内Ca²⁺参与调控灵芝三萜积累
Abscisic acid-mediated cytosolic Ca²⁺ modulates triterpenoid accumulation of Ganoderma lucidum
浙江大学学报（英文版）（B辑：生物医学和生物技术） 2023年24卷第12期页码：1174-1179
Affiliations：

College of Food Science, Shanxi Normal University, Taiyuan 030031, China
Funds：

the Applied Basic Research Project of Shanxi Province(202203021221135;201901D211402;202103021223255)
DOI：10.1631/jzus.B2300279
中图分类号：
CSTR：

崔美林,赵燚涛,张秀红等.脱落酸介导胞内Ca²⁺参与调控灵芝三萜积累[J].浙江大学学报（英文版）（B辑：生物医学和生物技术）,2023,24(12):1174-1179.

Meilin CUI, Yitao ZHAO, Xiuhong ZHANG, et al. Abscisic acid-mediated cytosolic Ca²⁺ modulates triterpenoid accumulation of Ganoderma lucidum[J]. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2023,24(12):1174-1179.
崔美林,赵燚涛,张秀红等.脱落酸介导胞内Ca²⁺参与调控灵芝三萜积累[J].浙江大学学报（英文版）（B辑：生物医学和生物技术）,2023,24(12):1174-1179. DOI： 10.1631/jzus.B2300279.

Meilin CUI, Yitao ZHAO, Xiuhong ZHANG, et al. Abscisic acid-mediated cytosolic Ca²⁺ modulates triterpenoid accumulation of Ganoderma lucidum[J]. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2023,24(12):1174-1179. DOI： 10.1631/jzus.B2300279.

摘要

灵芝是中医药宝库中的珍品，具有重要的药理学功能。作为灵芝最主要的活性物质之一，灵芝三萜含量是评价灵芝质量的重要指标。本研究旨在探讨脱落酸（ABA）介导胞内钙离子（Ca,2+,）对灵芝三萜积累的影响。研究发现，ABA （300 μmol/L）可有效促进灵芝三萜积累，其合成途径中关键酶基因（,sqs,、,hmgr,、,ls,）表达水平随之发生变化；同时，ABA诱导可激活胞内Ca,2+,通道并提高Ca,2+,浓度。在ABA介导下，外源Ca,2+,供体和抑制剂可直接影响胞内Ca,2+,浓度及Ca,2+,信号相关基因的表达。此外，ABA介导的Ca,2+,在灵芝三萜的生物合成中起着关键的调节作用，并伴随抗氧化防御调节，包括超氧化物歧化酶（SOD）和抗坏血酸过氧化物酶（APX）活性、超氧阴离子自由基（O,2,·-,）清除能力、谷胱甘肽（GSH）含量的提高。

Abstract

关键词

灵芝三萜脱落酸钙离子（Ca2+）信号抗氧化能力

Keywords

references

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脱落酸介导胞内Ca2+参与调控灵芝三萜积累

Abscisic acid-mediated cytosolic Ca2+ modulates triterpenoid accumulation of Ganoderma lucidum

DOI：10.1631/jzus.B2300279

摘要

Abstract

关键词

Keywords

references

脱落酸介导胞内Ca²⁺参与调控灵芝三萜积累

Abscisic acid-mediated cytosolic Ca²⁺ modulates triterpenoid accumulation of Ganoderma lucidum