A novel clinical data management platform for acute pancreatitis

Shiyin CHEN; Cheng ZHANG; Zhi'en WANG; Jian ZHANG; Wenqiao YU; Yanshuai WANG; Weiwei SI; Tingbo LIANG; Yun ZHANG

doi:10.1631/jzus.B2300539

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Correspondence | Updated：2024-08-19

A novel clinical data management platform for acute pancreatitis
A novel clinical data management platform for acute pancreatitis
一种新型的急性胰腺炎临床数据管理平台
Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology) Vol. 25, Issue 8, Pages: 711-718(2024)
Affiliations：

1.Department of Hepatobiliary and Pancreatic Surgery, Zhejiang Provincial Key Laboratory of Pancreatic Disease, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China
2.Department of Rehabilitation Medicine, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China
3.Department of Comprehensive Intensive Care Unit, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China
Funds：
DOI：10.1631/jzus.B2300539
CLC：
CSTR：
Published： 15 August 2024 ，

Received： 30 July 2023 ，

Revised： 06 March 2024 ，
Accepted：

陈诗音,张承,王志恩等.一种新型的急性胰腺炎临床数据管理平台[J].浙江大学学报（英文版）（B辑：生物医学和生物技术）,2024,25(08):711-718.

Shiyin CHEN, Cheng ZHANG, Zhi'en WANG, et al. A novel clinical data management platform for acute pancreatitis. [J]. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology) 25(8):711-718(2024)
陈诗音,张承,王志恩等.一种新型的急性胰腺炎临床数据管理平台[J].浙江大学学报（英文版）（B辑：生物医学和生物技术）,2024,25(08):711-718. DOI： 10.1631/jzus.B2300539.

Shiyin CHEN, Cheng ZHANG, Zhi'en WANG, et al. A novel clinical data management platform for acute pancreatitis. [J]. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology) 25(8):711-718(2024) DOI： 10.1631/jzus.B2300539.

摘要

急性胰腺炎是一种常见的消化系统疾病，其中重症急性胰腺炎治疗难度大且死亡率高，尚需进行大量临床研究。急性胰腺炎的诊治过程会产生大量的临床数据，而不同医疗中心的数据存在很大的异质性，这增加了临床研究的难度。因此，一个能够对真实世界数据实施结构化统一管理的单病种多中心数据平台将会成为一个提升急性胰腺炎相关临床研究的质量及进度的理想工具。该平台包含以下内容：临床数据的前结构化设定、数据录入/导入方式的设定、基于特征标记的同质病例检索功能、以诊治场景重现为特征的数据输出模式、数据安全及脱敏方式的设定、数据共享及利用方式的设定、随机对照试验（RCT）模块的搭载等。急性胰腺炎多中心临床数据管理平台的使用让医疗中心在急性胰腺炎的诊治和研究中获得了安全精准、结构统一、追溯可行、场景清晰、功能齐全的真实世界医疗数据，并且在开展多中心、高质量、多任务的临床研究的同时，实现了临床诊治及医师培训质量的提升。

Abstract

关键词

急性胰腺炎临床数据管理结构化数据多中心

Keywords

references

Abul-Husn NS, Kenny EE, 2019. Personalized medicine and the power of electronic health records. Cell, 177(1):‍58-69. https://doi.org/10.1016/j.cell.2019.02.039https://doi.org/10.1016/j.cell.2019.02.039

Botta M, Tsonas AM, Pillay J, et al., 2021. Ventilation management and clinical outcomes in invasively ventilated patients with COVID-19 (PRoVENT-COVID): a national, multicentre, observational cohort study. Lancet Respir Med, 9(2):139-148. https://doi.org/10.1016/S2213-2600(20)30459-8https://doi.org/10.1016/S2213-2600(20)30459-8

Boxhoorn L, Voermans RP, Bouwense SA, et al., 2020. Acute pancreatitis. Lancet, 396(10252):726-734. https://doi.org/10.1016/S0140-6736(20)31310-6https://doi.org/10.1016/S0140-6736(20)31310-6

Docherty AB, Mulholland RH, Lone NI, et al., 2021. Changes in in-hospital mortality in the first wave of COVID-19: a multicentre prospective observational cohort study using the WHO Clinical Characterisation Protocol UK. Lancet Respir Med, 9(7):773-785. https://doi.org/10.1016/S2213-2600(21)00175-2https://doi.org/10.1016/S2213-2600(21)00175-2

Finazzi S, Paci G, Antiga L, et al., 2020. PROSAFE: a European endeavor to improve quality of critical care medicine in seven countries. Minerva Anestesiol, 86(12):1305-1320. https://doi.org/10.23736/S0375-9393.20.14112-9https://doi.org/10.23736/S0375-9393.20.14112-9

Huang FF, Meng HB, Sun Y, et al., 2020. Factors causing abnormal heart failure after successful fluid resuscitation on acute pancreatitis patients. Pancreas, 49(4):e33-e35. https://doi.org/10.1097/MPA.0000000000001532https://doi.org/10.1097/MPA.0000000000001532

Johnson A, Bulgarelli L, Pollard T, et al., 2023. MIMIC-IV (Version 2.2). PhysioNet. https://doi.org/10.13026/6mm1-ek67https://doi.org/10.13026/6mm1-ek67

Ke L, Zhou J, Mao WJ, et al., 2022. Immune enhancement in patients with predicted severe acute necrotising pancreatitis: a multicentre double-blind randomised controlled trial. Intensive Care Med, 48(7):899-909. https://doi.org/10.1007/s00134-022-06745-7https://doi.org/10.1007/s00134-022-06745-7

Leppäniemi A, Tolonen M, Tarasconi A, et al., 2019. 2019 WSES guidelines for the management of severe acute pancreatitis. World J Emerg Surg, 14:27. https://doi.org/10.1186/s13017-019-0247-0https://doi.org/10.1186/s13017-019-0247-0

Pollard TJ, Johnson AEW, Raffa JD, et al., 2018. The eICU Collaborative Research Database, a freely available multi-center database for critical care research. Sci Data, 5:180178. https://doi.org/10.1038/sdata.2018.178https://doi.org/10.1038/sdata.2018.178

Schepers NJ, Bakker OJ, Besselink MG, et al., 2019. Impact of characteristics of organ failure and infected necrosis on mortality in necrotising pancreatitis. Gut, 68(6):‍1044-1051. https://doi.org/10.1136/gutjnl-2017-314657https://doi.org/10.1136/gutjnl-2017-314657

Yu WQ, Zhang Y, Zhang SY, et al., 2016. Impact of misplaced subclavian vein catheter into jugular vein on transpulmonary thermodilution measurement variables. J Zhejiang Univ-Sci B (Biomed & Biotechnol), 17(1):‍60-66. https://doi.org/10.1631/jzus.B1500167https://doi.org/10.1631/jzus.B1500167

Zhang SY, Liang ZY, Yu WQ, et al., 2014. Early enteral nutrition with polymeric feeds was associated with chylous ascites in patients with severe acute pancreatitis. Pancreas, 43(4):553-558. https://doi.org/10.1097/MPA.0000000000000067https://doi.org/10.1097/MPA.0000000000000067

Zhang Y, Gao SL, Zhang SY, et al., 2014. Six cases of severe acute pancreatitis complicated with vancomycin-resistant enterococcus enteritis. Shock, 42(5):400-406. https://doi.org/10.1097/SHK.0000000000000237https://doi.org/10.1097/SHK.0000000000000237

Zhang Y, Zhang SY, Gao SL, et al., 2015. Successful resolution of gastric outlet obstruction caused by pancreatic pseudocyst or walled-off necrosis after acute pancreatitis: the role of percutaneous catheter drainage. Pancreas, 44(8):1290-1295. https://doi.org/10.1097/MPA.0000000000000429https://doi.org/10.1097/MPA.0000000000000429

Zhang Y, Yu WQ, Zhang J, et al., 2020. Efficacy of early percutaneous catheter drainage in acute pancreatitis of varying severity associated with sterile acute inflammatory pancreatic fluid collection. Pancreas, 49(9):‍1246-1254. https://doi.org/10.1097/MPA.0000000000001666https://doi.org/10.1097/MPA.0000000000001666

Zhang Y, Zhang C, Yu WQ, et al., 2021. The “Two-Step” approach for classifying the severity of acute pancreatitis: a retrospective study. J Hepato-Biliary-Pancreat Sci, 28(10):902-912. https://doi.org/10.1002/jhbp.943https://doi.org/10.1002/jhbp.943

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